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Grants Portfolio - Active Awards
AFTD-ADDF Accelerating Drug Discovery for FTD
Mitigating TDP-43 loss of function and disease initiation in FTD thru repair of the Nuclear Pore and CHMP7/ESCRT3 dysfunction
Jeffrey Rothstein, MD, PhD | Johns Hopkins School of Medicine
2023
$269,967
TTBK1 inhibitors as new therapeutic approach for FTD and other related disorders
Ana Martinez, PhD | Ankar Pharmaceuticals
2022
$185,000
Selecting lead candidate REV-ERB agonist for the treatment of FTD
Robert Williams, PhD | Pelagos Pharmaceuticals
2022
$214,118
Discovery of selective LRP1 inhibitors to prevent tau uptake and spread
Kenneth Kosik, MD | University of California Santa Barbara
2020
$300,000
Development of PIKFYVE antisense oligonucleotides (ASO) treatment for FTD
Wen-Hsuan Chang, PhD | AcuraStem Inc.
2020
$165,000
Preclinical efficacy study for antibody therapy in C9orf72 FTD/ALS mice
Dieter Edbauer, MD | Deutschen Zentrums für Neurodegenerative Erkrankungen DZNE
2019
$300,000
AFTD-ADDF Diagnostics Accelerator
Neurofilament (Nf) as a Fluid Biomarker of Neurodegeneration in Familial Frontotemporal Degeneration (f-FTD)
Rohini Khillan, PhD | Foundation for the National Institutes of Health (FNIH)
2021
$250,000
Plasma pathologic TDP-43 as a biomarker for FTLD-TDP
Qinwen Mao, MD, PhD | The University of Utah School of Medicine
2021
$500,000
Plasma neuroinflammatory biomarkers for the diagnosis of dementia subtypes
Matthew Pase | Monash University
2021
$671,160
Remote blood biomarker monitoring in frontotemporal lobar degeneration: Neurofilament Surveillance Project (NSP)
Rodney Pearlman, PhD | The Bluefield Project to Cure FTD
October 2019
$1,200,000
FTD Biomarkers Initiative
Mapping neuroinflammation in frontotemporal lobar degeneration – development of a surrogate marker for early diagnosis and disease progression
Tammaryn Lashley, MD, PhD | UCL Institute of Neurology
2019
$1,102,133.19
Accelerating tau PET imaging through head to head comparison of novel radiotracers
Tammaryn Lashley, MD, PhD | UCL Institute of Neurology
2018
$247,272
Digital Assessment Tools for FTD and ALS
Harmonizing remote smartphone assessments of cognition, behavior, and motor functioning across the spectrum of FTD and ALS
Adam Staffaroni, PhD | UCSF
2023
$350,000
Digital Measurements of Motor and Voice Functions in FTD
Ashkan Vaziri, PhD | BioSensics
2023
$399,999
Target ALS Partnership
Identification of Small Molecule Inhibitors of TDP-43 Liquid-Liquid Phase Separation
James Shorter, PhD | Merck
2016
$850,000
Targeting G3BP1 and the stress granule response as a therapy for ALS & FTD
Dominique Cheneval, PhD | Novation Pharmaceuticals
2020
$723,175
Treat FTD Fund
Open-label Clinical Trial of Nabilone for Neuropsychiatric Symptoms in Frontotemporal Dementia
Simon Ducharme, MD | McGill University
2021
$1,399,077.51
Evaluating the effects of GLP-1 analog, oral semaglutide, as a treatment for sporadic behavioral variant frontotemporal dementia (bvFTD)
Paul Edison, MD | Imperial College London
2021
$3,000,000
Dopaminergic Therapy for Frontotemporal Dementia Patients
Giacomo Koch, PhD | Saint Lucia Foundation
2020
$602,800
Non-Invasive Brain Stimulation for Gamma Induction and Cognitive Enhancement in FTD
Emiliano Santarnecchi, PhD | Harvard Medical School
2019
$1,959,841
Non-invasive brain stimulation to restore cortical plasticity
Barbara Borroni, MD | University of Brescia
2017
$90,000
Pilot Grants
PATHWAYS OF HOPE
Integrated proteomics and phosphoproteomics across FTLD-TDP subtypes
Zachary McEachin | Emory University
2023
$110,000
PATHWAYS OF HOPE
Synthetic promoter screening to uncover determinants of FTD pathology
Zevik Melamed | Hebrew University of Jerusalem
2023
$110,000
WELL-BEING IN FTD
An ethical framework for disclosure of onset-predicting biomarkers in frontotemporal dementia
Eline Bunnik, PhD | Erasmus Medical Center
2023
$110,000
WELL-BEING IN FTD
Social Network Neuromodulation in Behavioral Variant Frontotemporal Dementia
Alexandru Iordan, PhD | University of Michigan
2022
$109,784
WELL-BEING IN FTD
Positive Behaviour Support (PBS) for individuals with frontotemporal dementia: increasing service and family capacity through a mentoring and training model
Alinka Fisher, PhD | Finders University
2021
$58,616
ISFTD Infrastructure Grant
John van Swieten, PhD | International Society for Frontotemporal Dementias (ISFTD)
2023
$250,000
Clinical Research Training Scholarship in FTD
Large-scale biofluid proteomics to identify disease progression biomarkers in C9orf72 frontotemporal dementia
Rowan Saloner, PhD | UCSF
2024
$150,000
Personalized HD-tDCS in Primary Progressive Aphasia
Tanav Popli, MD | University of Michigan
2023
$150,000
Multimodal evidence of the role of Alzheimer’s disease pathology in corticobasal and progressive supranuclear palsy syndromes
Indira García Cordero, PhD | University of Toronto
2022
$150,000
Holloway Postdoctoral Fellowships
Determining the Impact of TMEM106B Fibrils on Neurons
John Replogle, PhD | National Institute of Neurological Disorders and Stroke (NIH/NINDS)
2024
$120,000
Frontotemporal Dementia (FTD) and the Criminal Legal System: An Examination of Experiences and Policies
Victoria Helmly, PhD | Georgia State University
2024
$120,000
Targeting TDP-43 aggregation as therapeutics for ALS/FTD
Marc Shenouda, PhD | University of Toronto
2023
$120,000
Virtual Reality Social Cognition Game for Preclinical Frontotemporal Dementia
Jackie Poos | Erasmus Medical Center
July 2023
$115,123
Deciphering the consequence of ChromograninA (CgA) depletion in Tauopathy
Suborno Jati, PhD | Regents of the University of California
2022
$120,000
Long-read transcriptomics in FTLD-TDP to aid in the identification of novel biomarkers and mechanistic insights
Julia Faura Llorens, PhD | University of Antwerp
2022
$119,947
Active AFTD Awards
Translational Research
AFTD-ADDF Accelerating Drug Discovery for FTD
AFTD-ADDF Diagnostic Accelerator
Digital Assessment Tools for FTD and ALS
Holloway Fellowships
Clinical Research Training Scholarship in FTD
Holloway Postdoctoral Fellowship
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